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Research

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Welcome

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Our scientific profile

We are a motivated junior research group working at the Institute of Medical Virology at the Justus Liebig University Giessen.

Current research activities focus on the biology and pathogenesis of respiratory viruses (incl. corona- and influenza viruses).

The main goal of our studies is to obtain a comprehensive understanding of (host) factors and molecular mechanisms involved in viral replication. Information derived from these studies is used to develop new prophylactic and therapeutic strategies to combat respiratory and/or systemic infections caused by these viruses.

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Most important publications

Shaban MS*, Müller C*, Mayr-Buro C*, Weiser H, Meier-Soelch J, Albert BV, Weber A, Linne U, Hain T, Babayev I, Karl N, Hofmann N, Becker S, Herold S, Schmitz ML, Ziebuhr J, Kracht M. Multi-level inhibition of coronavirus replication by chemical ER stress. Nat Commun. 2021

Müller C , Hardt M, Schwudke D, Neuman BW, Pleschka S, Ziebuhr J. Inhibition of Cytosolic Phospholipase A2α Impairs an Early Step of Coronavirus Replication in Cell Culture. J Virol. 2018

Pfafenrot C*, Schneider T*, Müller C* , Hung LH, Schreiner S, Ziebuhr J, Bindereif A. Inhibition of SARS-CoV-2 coronavirus proliferation by designer antisense-circRNAs. Nucleic Acids Res. 2021 

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Funding

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